Painless artificial abortion
Conditions
Interventions
Group 1:remimazolam tosylate + sufentanil 0.05µg/kg
All patients were given intravenous sufentanil 0.05µg/kg in Group 1. The dose of remimazolam tosylate for the following patient was determined by t
Group 2:remimazolam tosylate + sufentanil 0.1µg/kg
All patients were given intravenous sufentanil 0.1µg/kg in Group 2. The dose of remimazolam tosylate for the following patient was determined by the
Sponsors
Guangzhou Women and Children's Medical Center Liuzhou Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 45 years (2) BMI 18 - 28 kg/m2 (3) ASA physical status I or II
Exclusion criteria
Exclusion criteria: (1) Allergy, intolerance or contraindication to drugs used in the study; (2) Use of Sedative or analgesic drugs within 24 hours; (3) Hepatic or renal malfunction (4) History of neurological, respiratory, or cardiac diseases (5) Participant received antipsychotic or hypnotic medications, alcohol or drug abuse; (6) Abuse of sedatives or analgesics (7) Definite difficult airway
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ED50 of remimazolam tosylate ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anesthesia induction time;recovery time;anesthesia satisfaction of surgeons and patients;dischargeable time;The incidence of respiratory depression;pain scores;m-YPAS score;Duration of surgery;side effects ; | — |
Countries
China
Contacts
Public ContactMo Xiaofei
Guangzhou Medical University Affiliated Women and Children's Medical Cente Guangzhou Women and Children Medical Center of Liuzhou Hospital
Outcome results
None listed