hepatocellular carcinoma
Conditions
Interventions
15min group:15 minutes per clamp
25min group:25 minutes per clamp
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Elective surgery patients 2.Adult males or females between the ages of 18 and 80 years old. 3.Preoperative imaging and test results suggestive of hepatocellular carcinoma. 4.No intrahepatic or extrahepatic metastases of hepatocellular carcinoma detected on preoperative imaging studies 5.Normal liver function or well-reserved function before operation (Child–Pugh classes A or B with the score = 7,ICG-R15<10%). 6.No other treatment prior to enrollment, such as operation, radiofrequency ablation (RFAB), TACE, targeted therapy, immunotherapy, liver transplantation. 7.Signed informed consent from the patient or legal guardian prior to enrollment in the study.
Exclusion criteria
Exclusion criteria: 1.Imaging of the presence of vascular invasion or extrahepatic metastases. 2.Combined heart, lungs, kidneys and other important organs serious organic lesions, the patient can not tolerate surgery 3.Previous treatment with targeted, immunological or interventional therapies 4.Unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2 year OS; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 year RFS;liver function (ALT /AST);Intraoperative haemorrhage;morbidity;mortality;1 year DFS;Surgical time;Length of postoperative stay; | — |
Countries
China
Contacts
Public ContactJiang li
West China Hospital of Sichuan University
Outcome results
None listed