lung cancer
Conditions
Interventions
Qi and Yin deficiency group:none
Qi deficiency and phlegm-dampness group:none
Sponsors
Tongde Hospital of Zhejiang Province
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Diagnosed as advanced non-small cell lung cancer after obtaining tissue pathology through lung tissue puncture, surgery, or cytological testing, and no driver gene mutations such as EGFR and ALK were required and clear PD-L1 TPS test results were obtained. 2. PD-L1 immunosuppressant monotherapy or combined with chemotherapy as the first-line treatment; 3. It is qi and Yin deficiency syndrome, qi deficiency and phlegm dampness syndrome or other syndrome types by TCM syndrome differentiation (preliminary screening through tongue diagnosis platform); 4. Age =40, =80 years old; 5. Karnofsky Performance Scale (KPS) =60; 6. Expected survival time =6 months; 7. Good compliance, can understand the situation of this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the inclusion criteria; 2. Patients with other primary malignancies or brain metastases at diagnosis; 3. Patients receiving systemic glucocorticoids (excluding daily glucocorticoid replacement therapy for adrenal or pituitary insufficiency) or other immunosuppressive therapy; 4. Patients with serious endocrine, cardiovascular, hematological, liver and kidney diseases; 5. Pregnant or lactating women and patients with mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Single cell omics;PFS;ORR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proteomics;Metabonomics;Intestinal flora; | — |
Countries
China
Contacts
Public ContactChai Kequn
Tongde Hospital of Zhejiang Province
Outcome results
None listed