Acute myocardial infarction
Conditions
Interventions
Test group:Drug eluting balloon implantation
Sponsors
The first hospital of Lanzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Acute myocardial infarction meeting PPCI criteria: ·>20 min chest pain, ST segment elevation of at least two adjacent leads by 1 mm, a new left bundle branch block or positive posterior wall myocardial infarction ·Reperfusion is expected to be feasible within 12 hours of onset Acute myocardial infarction with thrombolytic therapy within 6 hours and remedial PCI within 24 hours Meet the inclusion criteria of infarct related arteries of PPCI ·Primary coronary artery disease ·Reference vessel diameter = 2.5 mm and = 4 mm ·No severe calcification ·Diameter stenosis after thrombus aspiration and pre dilation shall not exceed 50% (visual inspection)
Exclusion criteria
Exclusion criteria: Age 75 years ·History of myocardial infarction ·Known contraindications / bivalirudin, fondaparinux sodium, heparin, aspirin, prasugrel and / or ticagrel ·Participate in another clinical study to interfere with this protocol ·Uncertain neurological outcomes, such as resuscitation ·Intubation / ventilation ·Cardiac shock before randomization ·Known intracranial diseases (mass, aneurysm, arteriovenous malformation, hemorrhagic CVA, ischemic CVA / TIA < 6 months ago, including or ischemic cerebrovascular disease (permanent neurological defect) ·Gastrointestinal / urinary tract bleeding within 2 months before inclusion ·Refuse blood transfusion ·Major surgery is planned within 6 weeks ·Stent implantation < 1 month before inclusion ·Life expectancy less than 12 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantitative Flow Ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major adverse cardiac events; | — |
Countries
CHINA
Contacts
Public ContactMing bai
The first hospital of Lanzhou University
Outcome results
None listed