Effect of esketamine on the quality of recovery after general anesthesia in children

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400083622

Enrollment

Unknown

Registered

2024-04-29

Start date

2024-05-01

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsil hypertrophy

Interventions

Control group:After the control group was included, normal saline was given during induction of general anesthesia, and the recovery quality of children after general anesthesia was assessed

Esketamine group:After inclusion in the esketamine group, esketamine was given during induction of general anesthesia to assess the quality of recovery after general anesthesia in children

Eligibility

Sex/Gender

All

Age

7 Years to 17 Years

Inclusion criteria

Inclusion criteria: (1) Age 7-17 years old (2)BMI 14-25 kg/m2 (3)ASA score is ? or II (4) Tonsil adenoidectomy under general anesthesia was performed (5) The guardian of the study object clearly understands and voluntarily participates in the study, and the informed consent is signed by the guardian of the study object

Exclusion criteria

Exclusion criteria: (1) Neuropsychiatric disorders (2) Heart and lung disease (3) Acute phase/recovery period of acute upper respiratory tract infection (4) History of chronic diseases (5) Take any sedative medication before surgery (6) Preterm birth (less than 36 weeks gestation) (7) Developmental delays (8) Any other conditions for which esketamine is not appropriate and which the investigator considers inappropriate for participation in the study (emergency surgery: hypovolemia, shock, or coma; Plan to use other anesthesia methods besides general anesthesia; Infectious heart disease; Abnormal clotting function, anemia or thrombocytopenia; Abnormal liver and kidney function; Allergic or contraindicated to esketamine, opioids, propofol, muscle relaxants and their components; People who are judged to have difficulty managing their respiratory tract)

Design outcomes

Primary

Measure	Time frame
Postoperative recovery quality;	—

Secondary

Measure	Time frame
Postoperative pain;Postoperative nausea and vomiting;	—

Countries

China

Contacts

Public ContactDelong Peng

Women and Children's Hospital of Ningbo University

504036542@qq.com+86 158 8859 4789

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026