diabetic foot ulcers
Conditions
Interventions
PEG-Loxenatide therapy group:Routine dressing change and PEG-Loxenatide therapy
Sponsors
Tongji Hospital,Jiefang Road 1095 Wuhan, Hubei Province
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) T2DM patients who meet the WHO 1999 diagnostic criteria; (2) The DFU classification adopts Wagner I-II level; (3) Age>18 years old; (4) First line routine treatment of diabetes wound failed to heal after 4 weeks
Exclusion criteria
Exclusion criteria: (1) Patients with DKA and hypertonic status; (2) Patients with lower limb arterial occlusion or ABI<0.60; (3) PEDIS grade 3-4 for foot infections; (4) Patients with severe coronary heart disease, cerebral infarction, heart failure, and renal failure; (5) Patients with malignant tumors, medullary thyroid carcinoma, and pancreatitis; (6) Patients with severe gastrointestinal diseases (7) Patients using immunosuppressive agents; (8) Pregnant and lactating women. (9) Patients participating in other clinical trials; (10) Researchers believe that other reasons are not suitable for clinical trial participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| wound area; | — |
Secondary
| Measure | Time frame |
|---|---|
| capillary density;tissue factor; | — |
Countries
China
Contacts
Public ContactShao Shiying
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed