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Heweiyangxue for the treatment of chemotherapy-related gastrointestinal reactions in lung cancer: a randomized controlled trial

Heweiyangxue for the treatment of chemotherapy-related gastrointestinal reactions in lung cancer: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083612
Enrollment
Unknown
Registered
2024-04-29
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer

Interventions

Treatment group:Chemotherapy and Heweiyangxue Granules
Control group:Chemotherapy and placebo granules

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? With clear histological or cytological pathology confirmed diagnosis of non-small cell lung cancer; ? Age =18 and <80 years old, regardless of gender; ?Eastern Cooperative Cancer Group (ECOG) physical status score 0-2, and expected survival =3 months; ? No serious organ function damage and meet the indications for chemotherapy; ? No mental abnormality or psychiatric disease; ? Patients understood the content of the study, voluntarily enrolled, and signed an informed consent form.

Exclusion criteria

Exclusion criteria: ?Have a clear history of allergy related to taking Chinese medicine; ? Those with severe, uncontrolled organic lesions or infections, such as decompensated cardiac, pulmonary, and renal failure, resulting in the inability to tolerate chemotherapy or those in poor general condition, unable to eat; ? Those who are unable to fill in the scale due to impaired consciousness or dyslexia; ? Participated in clinical trials of other drugs in the last 1 month or not yet finished.

Design outcomes

Primary

MeasureTime frame
MD Anderson Symptom Inventory-Traditional Chinese Medicine;

Secondary

MeasureTime frame
MASCC Antiemesis Tool;CRP;TNF-a;IL-6;IL-8;White blood cell;Red blood cell;Neutrophil;Hemoglobin;Platelet;Gastrin;Albumin;Prealbumin;Body Mass Index;Disease Control Rate;

Countries

China

Contacts

Public ContactLing Xu

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

xulq67@aliyun.com+86 159 0190 3361

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026