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Study on the role of Enrichment free WGS in the diagnosis and treatment of urinary tumors and calculi

Study on the role of Enrichment free WGS in the diagnosis and treatment of urinary tumors and calculi

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083609
Enrollment
Unknown
Registered
2024-04-29
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urinary tumors and calculi

Interventions

Gold Standard:urinary tumors: postoperative pathological biopsy Urinary calculi: CT of urinary system
Index test:Enrichment free WGS

Sponsors

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with suspected urological tumors (including kidney cancer, prostate cancer, upper urothelial cancer, bladder cancer), including hematuria and/or suspected space occupation; 2. Patients with suspected recurrent complex upper urinary tract calculi: (1) bilateral renal calculi with =2 calices; (2) Unilateral high-load multiple kidney stones (such as staghorn stones), stone distribution =2 calices, and postoperative stone composition analysis excluded infectious stones; ? In patients with multiple recurrence of stones, the number of recurrence of stones was =3 times; 3. Patients with rapid recurrence of stones recurred within two years after removal of stones. 4. Early onset adult patients with kidney stones (age of onset 18-25 years).

Exclusion criteria

Exclusion criteria: 1: Under the age of 18 2: Individuals who do not want to sign consent forms or provide morning urine tests or medical records to participate in this trial 3: There are already individuals with indwelling catheters

Design outcomes

Primary

MeasureTime frame
Specificity of urinalysis by Enrichment-free WGS analysis;Sensitivity of urinalysis by Enrichment-free WGS analysis;

Secondary

MeasureTime frame
Relationship between positive for Enrichment-free WGS tests and clinicopathological parameter;

Countries

China

Contacts

Public Contactwang shaogang

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

sgwangtjm@163.com+86 133 6725 5851

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026