early esophageal cancer
Conditions
Sponsors
Department of Gastroenterology, Second Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients who meet the requirements of Article 1 and any of Articles 2-5 can be included: (1) aged 40-75 years old, male or female; (2) people in areas with high incidence of esophageal cancer; (3) previous pre-cancerous or precancerous esophageal diseases such as chronic esophagitis, Barrett's esophagus, esophageal mucosal leukomalacia, esophageal diverticulum, pancreatic achalasia, reflux esophagitis, etc.; (4) first-degree relatives of patients with esophageal cancer; and (5) the presence of other high-risk factors for esophageal cancer: preference of high-temperature and pickled foods, eating too fast, Smoking, heavy drinking (=15g/d), missing teeth, etc.
Exclusion criteria
Exclusion criteria: (1) Patients who have undergone surgical resection of esophagus, percutaneous endoscopic gastrostomy (PEG), chemotherapy and other invasive treatments (except for endoscopic treatment ); (2) Patients with TMN classification of carcinoma that meets the diagnosis of progressive carcinoma of T2 or above; (3) Patients who cannot be biopsied if they have taken anticoagulants, antiplatelets, or blood activating drugs within two weeks; (4) Women with PPI or H2 receptor antagonist; (5) patients with a history of malignant tumors or severe cardiac, pulmonary, hepatic or renal insufficiency, or severe mental disorders, etc.; (6) women who are pregnant or breastfeeding; and (7) those who are unable to cooperate with the examination and have not signed the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy;negative predictive value;Kappa value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;specificity;positive predictive value; | — |
Countries
China
Contacts
Public ContactDou weijia
Department of Gastroenterology, Second Affiliated Hospital of Air Force Medical University
Outcome results
None listed