T-ALL
Conditions
Interventions
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 90 Years
Inclusion criteria
Inclusion criteria: (i) Age =14 years; (ii) Diagnosis meets the criteria for T-ALL in the Blood Diagnostic and Therapeutic Criteria (Fourth Edition); (iii) All were treated with a modified dual-epi multi-targeting regimen, with the following specific dosages: cedarbenazine 30mg biw; azacitidine 75mg/m2 d1-d7; ;Venetoclax 100mg d1, 200mg d2, 300mg d3, 400mg qd d4-d14; dexamethasone 10mg d1-d7/d1-d10. The specific application dose is appropriately increased or decreased according to the patient's physical condition.
Exclusion criteria
Exclusion criteria: (i) women who are preparing for pregnancy, pregnant or breastfeeding; (ii) patients with serious underlying diseases of important organs, progressive tumors and other diseases that affect the prognosis of the treatment; (iii) poor adherence, inability to cooperate with the treatment, and any conditions that, after evaluation by the investigator, may increase the risk to the subject or interfere with the results of the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete remission rate, CR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression free survival, PFS;Overall survival, OS; | — |
Countries
China
Contacts
Public ContactLi Hui
Sichuan Provincial People's Hospital
Outcome results
None listed