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Based on functional near infrared spectroscopy, the effect of acupuncture on brain network activation in patients with consciousness disorder after brain injury was studied

Based on functional near infrared spectroscopy, the effect of acupuncture on brain network activation in patients with consciousness disorder after brain injury was studied

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083564
Enrollment
Unknown
Registered
2024-04-28
Start date
2024-05-03
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Consciousness disorder after traumatic brain injury

Interventions

Experimental group (Patients with consciousness disorders after traumatic brain injury):acupuncture
control group (Healthy individuals):acupuncture

Sponsors

The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) The new brain trauma was diagnosed by head imaging and met the evaluation criteria of consciousness disorder. 2) After 3 days of surgical treatment, there are still conscious disorders, and the score of Glasgow Coma Scale (GCS) is less than 13. It is estimated that the ICU stay will be no less than 14 days. At present, the condition is stable, with no serious infection and stable vital signs. 3) Consciousness was clear before injury, and there was no primary disturbance of consciousness and serious cerebrovascular disease. 4) the age is 18 ~ 60 years old. 5) No skull defect. 6) The family members signed the informed consent form and volunteered to participate in the study. 7) No acupuncture treatment was performed in the last 2 weeks. 8) No contraindications to acupuncture: needle sickness, hemophilia, severe skin infection, etc.

Exclusion criteria

Exclusion criteria: 1) Do not meet the standards of brain trauma and disturbance of consciousness, with unstable vital signs, severe infection and death risk. 2) Intracranial infection (the patient still has fever and abnormal cerebrospinal fluid within one week), and there is the possibility of reoperation. 3) Multiple injuries accompanied by limb fractures or skin and skull defects. 4) Patients with severe cardiovascular and cerebrovascular diseases before onset. 5) Patients and their families do not agree to participate in the study.

Design outcomes

Primary

MeasureTime frame
Oxygen and hemoglobin concentration;Brain functional connection strength;

Countries

CHINA

Contacts

Public ContactZhu Zhiwen

The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine

997128816@qq.com+86 185 0581 5719

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026