diabetic kidney disease
Conditions
Interventions
the experimental group:Western standard treatment with Yishentongluo therapy
the control group:Western standard treatment
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic, staging, and syndrome determination criteria for DKD; 2. Age between 18 and 75 years (including 18 and 75 years old); 3. eGFR=15ml/min/1.73m2; 4. Glycated hemoglobin (HbA1c)<= 9.0%; 5. Has not ever received renal replacement therapy; 6. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. With non-diabetic kidney disease; 2. Severe infection, anemia, or electrolyte imbalance in the previous four weeks; 3. Patients with acute kidney injury, oliguria or anuria, severe edema, massive pleural or peritoneal effusion; 4. Use of corticosteroids or immunosuppressants in the previous three months; 5. Severe cardiac, cerebral, hepatic, or hemorrhagic diseases, including stroke, transient ischemic attack, significant neurological dysfunction remaining after stroke, myocardial infarction, unstable angina, ischemic heart disease with coronary artery bypass or PCI surgery, congestive heart failure (cardiac function class III-IV, NYHA rating), hepatic inadequacy with aspartate transaminase(AST) or alanine aminotransferase (ALT) levels more than twice the normal upper limit, severe thrombocytopenia (PLT <10×10^9/L, abnormal coagulation, or active gastrointestinal bleeding; 6. Accompanied with consumptive diseases such as tuberculosis or a history of psychiatric diseases; 7. Pregnant or women preparing for pregnancy or lactation; 8. Individuals who are currently participating in other intervention clinical trials or have participated in other clinical trials within 12 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour urinary protein;Estimated glomerular filtration rate (eGFR); | — |
Secondary
| Measure | Time frame |
|---|---|
| UACR, Scr;Traditional Chinese Medicine symptom score; | — |
Countries
China
Contacts
Public ContactMengdi Wang
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Outcome results
None listed