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Study of the Role of Host/Organ Unregulated Response in Septic Multiple Organ Dysfunction

Study of the Role of Host/Organ Unregulated Response in Septic Multiple Organ Dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083553
Enrollment
Unknown
Registered
2024-04-28
Start date
2024-05-15
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

none:none

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age > 18 years old; 2. Patients diagnosed with SEPSIS according to SEPSIS 3.0; 3. Patients with estimated hospital stay exceeding 72 hours.

Exclusion criteria

Exclusion criteria: 1. Age < 18 years old; 2. Patients or family members refuse to undergo ultrasound examination; 3. Cardiac ultrasound, lung ultrasound, snuff bottle artery ultrasound, liver ultrasound, kidney ultrasound, gastrointestinal ultrasound images cannot be obtained.

Design outcomes

Primary

MeasureTime frame
Age;Sex;Height;Weight;APACHE ? score;SOFA score;Admission Time;ICU Entry Time;Admission diagnosis;Principal disease or injure;Basic disease;Body temperature;Heart rate;Heart rhythm;Respiratory rate;Finger oxygen saturation;Noninvasive blood pressure;Arterial blood pressure;Pupil morphology;Pupillary light reflex;Central venous pressure;Peripheral perfusion index;Intracranial pressure;Intra-abdominal pressure;Blood glucose;GCS score;Sedation scale;Pain score;Delirium assessment;Intake (venous and gastrointestinal);Output (Urine volume);Output (Ultrafiltration volume of renal replacement therapy);Output (Stool volume);Output (Gastric residual volume);Total intake;Venous Intake;Gastrointestinal intake;Total output;Urine volume;Stool volume;Gastrointestinal decompression;Volume of drainage;Ultrafiltration volume of renal replacement therapy;Methods and intensity of Respiratory support;Methods and intensity of circulation support;Kinds of medicine and nutrition;Dose of medicine and nutrition;Frequency of medicine and nutrition;Placement and extraction of catheter;Host/Organ response index of Sepsis;Index and image of Echocardiogram;Index and image of Liver ultrasound;Index and image of Renal ultrasonography;Index and image of Gastrointestinal ultrasound;Index and image of Lung ultrasound;White blood cell count;Neutrophil absolute value;lymphocyte absolute value;Interleukin-6;Interleukin-8;Interleukin-10;Interleukin-12;Procalcitonin;C reactive protein;Tumor necrosis factor a;Ferritin;Serum amyloid protein;Antistreptolysin O;a1-acidglycoprotein;Serum prealbumin;a-1-antitrypsin;Thrombomodulin;Prothrombin time;Activated partial thromboplastin time;International normalised ratios;Thrombin time;Protein C;Protein S;Von Willebrand Factor;Antithrombin-3;Fibrinogen;Thrombelastogram;Activated Clotting Time;Clot rate;Platelet function;Fibrinogenase-a2-plasmin inhibitor complex;Recombinant Human tissue plasminogen activator-inhibitor complex;Thrombin-antithrombin complex;Fibrin degra

Countries

China

Contacts

Public ContactYin Wanhong

West China Hospital of Sichuan University

yinwanhong@wchscu.cn+86 135 1810 6758

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026