obesity
Conditions
Interventions
Normal Body weight group:NA
Sponsors
Sir Run Run Hospital, Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. 18= age = 85 years old, obese or normal body type: 18.5< BMI= 24.0 is normal, 24.0< BMI=28.0 is overweight, BMI=28.0 is obese, BMI unit kg/m²; 2. Stable weight (weight fluctuation <5% in the 3 months before enrollment); 3. Signed informed consent form and complied with the research protocol
Exclusion criteria
Exclusion criteria: 1. Those who suffer from endocrine diseases and are being treated and are not controlled; 2. In the past 3 months, you have taken drugs that affect your weight (such as orlistat, glucocorticoids, etc.) or drugs that affect appetite and gastrointestinal motility; 3. Severe liver function injury (ALT = 3ULN); Severe renal insufficiency (eGFR =60ml/min/1.73m2), heart failure (NYHA stage III.~IV.), severe hematologic system diseases (e.g., thalassemia, iron deficiency anemia, etc.); 4. The amount of ethanol equivalent to alcohol consumption is greater than 140g/week (70g/week for women>); 5. Those who are unable to cooperate with mental disorders; 6. Those who cannot eat by mouth; 7. Pregnant and lactating women; 8. History of tumor within 5 years; 9. Those who are judged by the researcher to be unsuitable to participate in this project.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight;BMI;Fasting glucose level;NAFLD;bone density;Cardiovascular event;Food intake; | — |
Secondary
| Measure | Time frame |
|---|---|
| TG;TC;HDL-C;Body fat ratio;Inflammatory factor; | — |
Countries
China
Contacts
Public ContactYu Liu
Sir Run Run Hospital of Nanjing Medical University
Outcome results
None listed