Diseases requiring tracheoscopy
Conditions
Interventions
test group:After slow intravenous injection of alfentanil (10ug/kg), ramazolam benzenesulfonate (0.2-0.3 mg /kg) was pushed for >60s to a modified alertness/sedation score (MOAA/S score) of 1-2 points
control group:After slow intravenous injection of alfentanil (10ug/kg), propofol (1-2mg/kg) was pushed for >60s to a modified alertness/sedation score (MOAA/S score) of 1-2 and then propofol was pumpe
Sponsors
Shaoxing People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients undergoing elective bronchoscopy, age 18-75 years, ASA = grade III, BMI = 30 kg/m2
Exclusion criteria
Exclusion criteria: With inadequately controlled potentially life-threatening circulatory and respiratory diseases; patients with allergies to benzodiazepines or other anesthetic drugs; patients with neurologic and psychiatric disorders; long-term use of sedative or antidepressant medications; a history of alcoholism or drug dependence; and patients who refuse to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| MOAA sedation score = 2 points Time;MOAA sedation score per half minute at the end of induction;MOAA sedation score when peak sedation is reached;MOAA sedation score every 1 minutes after reaching peak sedation;Full awakening time from last dose (MOAA = 5);Blood pressure, heart rate, oxygenation during anesthesia or sedation ; | — |
Countries
China
Contacts
Public ContactChen Zhonghua
Shaoxing People's Hospital
Outcome results
None listed