Stroke
Conditions
Interventions
Transcranial ultrasound stimulation group:10 sessions of transcranial ultrasound stimulation over two weeks and traditional limb rehabilitation
Pseudo ultrasound stimulation group:10 sessions of pseudo-ultrasound stimulation over two weeks and traditional limb rehabilitation
Sponsors
Shanghai Ruijin Rehabilitation Hospital Ethics Committee
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) patients with ischemic cerebral infarction confirmed by magnetic resonance; 2) age =35 years and =65 years; 3) onset time of 14-28 days; 4) presence of sequelae of limb movement disorders; 5) mRS score of 3-5; 6) absence of serious underlying diseases such as malignancy, cardiac failure, and severe hepatic and renal insufficiency; 7) consent to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) hemorrhagic transformation of the infarct focus; 2) ipsilateral limb hemiparesis or disability already existed before this onset; 3) presence of other intracranial pathologies, such as intracranial tumors, infections, etc.; 4) previous history of major neuropsychiatric disorders, such as epilepsy, dementia, Parkinson's disease, schizophrenia, anxiety disorders, depression, etc.; 5) severe stroke (NIHSS = 26 points) with life-threatening conditions and contraindications to rehabilitation; 6) mild stroke (NIHSS = 3 points) with mild, non-disabling symptoms and less likely to leave sequelae of limb movement disorders; 7) number of cerebral microhemorrhages = 10.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRS scores of 0-2; | — |
Secondary
| Measure | Time frame |
|---|---|
| 14-day and 90-day NIHSS score and Barthel score;Proportion of patients with an mRS score of 0-2 at 90-day follow-up;90-day mRS score;Includes 5 minutes of resting-state EEG and approximately 28 minutes of EEG under the exercise attempt task; | — |
Countries
China
Contacts
Public ContactGu Lin
Shanghai Ruijin Rehabilitation Hospital
Outcome results
None listed