Skip to content

Effects of transcranial alternating current stimulation combined with rehabilitation on motor function after stroke

Effects of high definition transcranial alternating current stimulation combined with rehabilitation therapy on upper limb function and cognition after stroke

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083526
Enrollment
Unknown
Registered
2024-04-26
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Experimental group:On the basis of conventional treatment to add tACS stimulation, parameter setting stimulation site for the affected side of the M1 area, frequency 20hz, current intensity 2mA, treat
set aside the hair inside the base of the electrode tray, exposing the scalp (use alcohol swabs to degrease the scalp inside the base to reduce the human impedance))
use the equipped syringe to suck up about 8 ml of conductive paste, and then injected the conductive paste into the base of the 5 electrode trays
put in the ring electrodes (black side up) electrode wires from the edge of the electrode tray openings led
screw the electrode tray top cover. Screw the top cover of the electrode holder. (iii) Positioning: The target point of treatment can be quickly localized by the EEG cap equipped by the manufacturer,
Control group:Conventional rehabilitation training mainly included physical therapy, occupational therapy, physiotherapy, acupuncture, hyperbaric oxygen and other conventional rehabilitation treatment

Sponsors

the Affiliated Suzhou Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Meet the diagnostic criteria for stroke established by the 4th National Cerebrovascular Symposium; ? 18 years old = age = 80 years old; ? first time onset of disease, the site of onset of disease is the basal ganglia region; ? The selected individual or their family members sign an informed consent form.

Exclusion criteria

Exclusion criteria: ? Patients with other neurological diseases that cause physical dysfunction; ? patients with serious cognitive impairment, speech disorder, mental disorder, and consciousness disorder who cannot cooperate; ? patients with contraindications to the treatment of TMS and tACS, such as cardiac pacemakers, intracranial and therapeutic areas with metal implantation, or cranial defects; and ? patients who are taking medications that have an effect on the excitability of the cortex,(including tricyclic antidepressants, nerve blockers, and anti-epileptic medications, etc.).

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Scale Assessment (FMA);EEG;

Secondary

MeasureTime frame
Berg Balance Scale;Action Research Arm Test ;Modified Barthel Index;Motor Evoked Potential ;

Countries

China

Contacts

Public ContactLiao Xiaoyu

Department of Rehabilitation Medicine, the Affiliated Suzhou Hospital of Nanjing Medical University

xiaoyuliao06@163.com+86 187 5131 1502

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026