esophageal cancer
Conditions
Interventions
Gold Standard:Gastrointestinal endoscopy and/or pathological diagnosis
Index test:Qualitative detection of MT-1A gene ,Epo gene and Septin9 gene methylation in human plasma.
Sponsors
Cancer Hospital Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) The sample information is complete, including sample medical record number, gender, age, clinical diagnosis information, etc.; 2) The plasma volume is not less than 2.0mL, and the blood sample is visually observed, and there is no visible turbidity or insoluble matter; 3) The subject signs an informed consent Book. 4) Anyone who meets one of the following conditions can be enrolled, as follows: ? People who are preparing for esophageal cancer surgery or esophagoscopy and have no history of esophageal cancer surgery or radiotherapy and chemotherapy; ? People who have been diagnosed with or without other esophageal diseases Population; ? People who have been diagnosed with other cancers; ? Some subjects whose plasma volume meets 4.0mL are enrolled (assessment reagent testing and first-generation sequencing are performed at the same time); ? Some subjects who are the same before and after surgery are enrolled.
Exclusion criteria
Exclusion criteria: 1) Samples that were not collected and stored in accordance with the [Sample Collection Requirements]; 2) The sample size is insufficient to complete the test; 3) The sample information is incomplete (including sample medical record number, gender, age, clinical diagnosis information, etc.); 4) Researchers think any other situation where it is considered inappropriate to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity;Specificity;Kappa value; | — |
Countries
China
Contacts
Public ContactLi Yin
Cancer Hospital Chinese Academy of Medical Sciences
Outcome results
None listed