bowel preparation
Conditions
Interventions
control group:On the morning of the examination, 2 boxes of compound polyethylene glycol electrolyte powder were taken orally, dissolved in 3000 mL of warm water to make a solution, and taken within 2
Observation group A:Take 1 tablet of linaclotide at 7:00~8:00 two days before the examination, and then take 2 boxes of compound polyethylene glycol electrolyte powder orally at 7:00~9:00 on the exami
Observation group B:Take 1 tablet of linaclotide each at 7:00~8:00 four days before the examination, and then take 2 boxes of compound polyethylene glycol electrolyte powder orally at 7:00~9:00 on the
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Colonoscopy patients aged 18-75 years (2) Constipation patients who meet the diagnostic criteria of Rome IV
Exclusion criteria
Exclusion criteria: (1) Patients with a history of allergies to the drugs in this study (2) Patients with severe heart, liver, and kidney diseases (3) Patients taking other gastrointestinal motility drugs, laxatives, antidiarrheal drugs, etc. within the past 2 weeks (4) Combining high blood pressure Patients with blood pressure, diabetes, intestinal obstruction, intestinal perforation and electrolyte imbalance, active inflammatory bowel disease (5) history of colorectal resection (6) history of taking linaclotide within 7 days (7) history of mental illness and unable to cooperate 8. Pregnant women and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Boston bowel preparation scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection rate of colon adenoma;Evaluation of adverse reactions; | — |
Countries
China
Contacts
Public ContactGu Sai
Chongqing Medical University
Outcome results
None listed