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Study on risk factors of platelet-rich plasma in the treatment of knee osteoarthritis

Study on risk factors of platelet-rich plasma in the treatment of knee osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083509
Enrollment
Unknown
Registered
2024-04-26
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Interventions

Trail group:None

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with knee osteoarthritis according to the 'Chinese guideline for diagnosis and treatment of osteoarthritis(2021 edition)' published in the Chinese Journal of Orthopaedics: Individual meet criteria of 1) + ( any two of 2), 3), 4), 5)) can be diagnosed: (1) Repeated knee pain in the past 1 month; (2) X-ray film (standing position or weight-bearing position) showed narrowed joint space, subchondral bone sclerosis and/or cystic degeneration, osteophyte formation at joint edge; (3) Age >= 50 years old; (4) Stiffness at morning = 40; 3. Received PRP treatment at least one time; 4. Under 80 years old;

Exclusion criteria

Exclusion criteria: 1. Combine one or more non-knee problems in lower limb that affect daily activities; 2. Intra-articular injection of steroids or PRP and other biological agents within 8 weeks; 3. Recieved other treatments that may have an impact on the observation indicators of PRP treatment in the past year, such as biological therapy including stem cells, and systemic immunosuppressive drugs;

Design outcomes

Primary

MeasureTime frame
VAS;the Western Ontario and McMaster UniversitiesOsteoarthritis Index, WOMAC;

Secondary

MeasureTime frame
safety;Continuous remission rate and cause of symptom induction;

Countries

China

Contacts

Public ContactHongchen He

West China Hosipital of Sichuan University

hxkfhhc@126.com+86 189 8060 2262

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026