Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with knee osteoarthritis according to the 'Chinese guideline for diagnosis and treatment of osteoarthritis(2021 edition)' published in the Chinese Journal of Orthopaedics: Individual meet criteria of 1) + ( any two of 2), 3), 4), 5)) can be diagnosed: (1) Repeated knee pain in the past 1 month; (2) X-ray film (standing position or weight-bearing position) showed narrowed joint space, subchondral bone sclerosis and/or cystic degeneration, osteophyte formation at joint edge; (3) Age >= 50 years old; (4) Stiffness at morning = 40; 3. Received PRP treatment at least one time; 4. Under 80 years old;
Exclusion criteria
Exclusion criteria: 1. Combine one or more non-knee problems in lower limb that affect daily activities; 2. Intra-articular injection of steroids or PRP and other biological agents within 8 weeks; 3. Recieved other treatments that may have an impact on the observation indicators of PRP treatment in the past year, such as biological therapy including stem cells, and systemic immunosuppressive drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;the Western Ontario and McMaster UniversitiesOsteoarthritis Index, WOMAC; | — |
Secondary
| Measure | Time frame |
|---|---|
| safety;Continuous remission rate and cause of symptom induction; | — |
Countries
China
Contacts
West China Hosipital of Sichuan University