Pediatric Acute Liver Failure
Conditions
Interventions
Trail group:no
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) Children admitted to the Pediatric Intensive Care Unit (PICU) of the First Hospital of Jilin University, diagnosed with pediatric acute liver failure and treated with plasma exchange, between January 2015 and May 1, 2023. Diagnostic criteria for pediatric acute liver failure: ? Children without a history of chronic liver disease who develop liver damage, and severe liver dysfunction occurs within 8 weeks of clinical liver disease onset; ? Coagulation disorders that cannot be corrected with vitamin K1 injection; ? Prothrombin time (PT) > 20s or International Normalized Ratio (INR) > 2.0, without hepatic encephalopathy; or with hepatic encephalopathy, PT > 15s or INR > 1.5. (2) Age between 28 days and 16 years old.
Exclusion criteria
Exclusion criteria: (1) Patients with incomplete information. (2) Individuals who discontinued treatment midway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical outcomes at discharge;Prothrombin time; | — |
Countries
China
Contacts
Public ContactYang Chunfeng
The First Hospital of Jilin University
Outcome results
None listed