Stroke
Conditions
Interventions
Suprahyoid muscle iTBS group:iTBS stimulation: stimulation intensity 100% RMT, each pulse contains 3 continuous pulses, 50Hz, 5Hz, each cluster for 2s, 8s interval, total time 192s, total stimulation
false stimulation: flip coil, treatment site, treatment parameters, etc
Bilateral swallowing cortical iTBS group:iTBS stimulation: stimulation intensity 100% RMT, each pulse contains 3 continuous pulses, 50Hz, 5Hz, each cluster for 2s, 8s interval, total time 192s, total
Combined stimulation group:iTBS stimulation: stimulation intensity 100% RMT, each pulse contains 3 continuous pulses, 50Hz, 5Hz, each cluster for 2s, 8s interval, total time 192s, total stimulation pu
Sponsors
The Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Unilateral stroke (hemorrhagic (without craniotomy), ischemic) meeting stroke diagnostic criteria; (CT or MRI confirmation, reserved for further subgroup analysis); (2) First onset, 2 weeks =3 level; (6) The family members or the patient himself shall sign the relevant informed consent.
Exclusion criteria
Exclusion criteria: (1) Swallowing problems caused by other neurological diseases, such as Parkinson's disease, Alzheimer's disease, motor neuron disease, craniocerebral trauma, cerebellar or brainstem stroke; (2) a history of intractable infectious disease; (3) intracranial metal implants and (or) cardiac metal implants; (4) Vvital signs are unstable or in the acute stage of disease; (5) The patient has poor cognitive function and cannot cooperate with the relevant examination and treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| standard swallowing function evaluation scale (SSA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Supraphyhyoid group motor evoked potential (MEP);Fiberoptic laryngoscope swallowing function examination (FEES);Functional near-infrared spectroscopy (fNIRS);Functional nuclear magnetic resonance (fMRI); | — |
Countries
China
Contacts
Public ContactBangqiang Hou
The Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed