adults with ADHD and/or major depressive disorders
Conditions
Interventions
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) 18-45 years of age; 2) Diagnosed by an attending psychiatrist or higher who meets the DSM-5 diagnostic criteria for ADHD (current) and/or MDD (current or past) in adults; (3) The patient with MDD has a DSM-5 diagnosis of "psychomotor retardation" or "reduced ability to think or concentrate or indecisiveness"; (4) HAMD-24 score = 20; 5) Unmedicated; the dose of medication has not been adjusted in the last 4 weeks and has remained unchanged during the study.
Exclusion criteria
Exclusion criteria: 1) Suffering from a mental disorder other than ADHD, MDD, or anxiety spectrum disorder; 2) Have neurological disorders such as history of epilepsy, history of traumatic brain injury, or serious physical illness; 3) Being pregnant or breastfeeding; 4) Severe suicidal ideation (score =3 on the suicide item of the HAM-D) and recent presence of self-injurious behavior; 5) Those with an intelligence level below the normal range, i.e., a total IQ score of less than 90 on the Wechsler Intelligence Test; 6) A frontal skin condition that may impede light penetration, such as tattoos or birthmarks; 7) Receiving photosensitizing medication within 14 days; 8) Have implants in the head, such as endovascular stent placement, to prevent possible dislocation associated with vasodilation; 9) Undergoing psychotherapy or other physical therapy methods.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy and response time for N-back tasks; | — |
Secondary
| Measure | Time frame |
|---|---|
| CPT-IP signal detection index;24-Item Hamilton Depression Scale (HAMD-24) Score; | — |
Countries
China
Contacts
Public ContactQian Qiujin
Peking University Sixth Hospital
Outcome results
None listed