Metabolic associated fatty liver disease
Conditions
Interventions
Digital intervention group:A comprehensive intervention based on exercise intervention through a digital platform for 3 months
Active-control group:Self-supervised for 3 months
Sponsors
Jiangsu Province Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with MAFLD in the outpatient department. 2.24kg/m^2 = 238 dB/m. 5.Weekly drinking volume (alcohol content) in the past half year was <140g for men and <70g for women. 6.Ability to act independently; able to actively cooperate with doctors' follow-up and conduct regular review according to medical advice. 7.Voluntary signed the informed consent, agreed and actively cooperated with this study.
Exclusion criteria
Exclusion criteria: 1.Patients with viral hepatitis, drug hepatitis, alcoholic fatty liver, organ failure, severe liver and renal insufficiency. 2.Patients with severe hypertension, heart disease, diabetes mellitus, mental and neurological diseases, motor dysfunction and other exercise contraindications. 3. Patients who have undergone bariatric surgery in the past 1 year or have taken weight-loss drugs in the last 3 months and lost more than 10% of their body weight. 4.Patients or family members are unable to perform digital intervention programs using smartphones.Patients or family members lack the fundamental digital literacy required to engage with digital intervention programs via smartphones, including the ability to install apps, upload data, and navigate the platform. 5.Subjects are also participating in other clinical research trials. 6.Claustrophobia, patients too large to enter the MRI scanner, and patients with MRI contraindications (such as certain metal implants).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver MRI proton density fat fraction (MRI- PDFF); | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function;Blood lipid;Blood glucose;LSM value measured by FibroScan;Anthropometric parameters;Body composition;Blood pressure;Compliance; | — |
Countries
China
Contacts
Public ContactZhu Yi
Jiangsu Province Hospital
Outcome results
None listed