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Research on Trauma intervention and Mechanism of with postpartum posttraumatic stress disorder based on Electroencephalograph and Magnetic Resonance Imaging

Research on Trauma intervention and Mechanism of with postpartum posttraumatic stress disorder based on Electroencephalograph and Magnetic Resonance Imaging

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083460
Enrollment
Unknown
Registered
2024-04-25
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postpartum posttraumatic stress disorder

Interventions

EMDR treatment group :Eye movement desensitization reprocessing (EMDR)
Healthy control:None

Sponsors

Department of Psychiatry, the Second XiangYa Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. EMDR treatment group and waiting list group: There were 50 PTSD patients in each group. Inclusion Criteria: 1) Meet the diagnostic criteria for current PTSD within 6 months of delivery; 2) Age 18-45 years old; 3) Right-handed; 4) Voluntarily participate in this study, and have fully understood the purpose, method, process, possible discomfort and risks of the experimental project, and sign the informed consent form. 2. Control group: 50 control participants. 1) within 6 months after delivery, did not meet the diagnostic criteria for DSM-5 PTSD, and did not take any medication for one month prior to enrollment; 2) Age 18-45 years; 3) Right-handed; 4) Voluntarily participate in this study, and have fully understood the experimental purpose, method, process, possible discomfort and risks of the experimental project, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. EMDR treatment group and waiting list group: 1) Current or previous serious neurological disease; 2) Current or previous meeting DSM-5 diagnostic criteria for substance abuse and dependence, mental retardation, schizophrenia, bipolar disorder and other psychiatric disorders; 3) A history of severe mental illness in a first-degree relative; 4) There are metal implants in the body. 2. Control group: 1) Current or previous serious physical or neurological illness; 2) have a current or previous psychiatric disorder consistent with a DSM-5 diagnosis; 3) A history of severe mental illness in a first-degree relative; 4) There are metal implants in the body.

Design outcomes

Primary

MeasureTime frame
PTSD Checklist for DSM-5 (PCL-5);Clinician-Administered PTSD Scale for DSM–5;Hamilton Anxiety Scale(HAMA);Hamilton depression scale (HAMD);Childhood trauma questionnaire, CTQ-SF;Impact of Event Scale-Revised, IES-R;Dissociative Experiences Scale-II, DES-II;Patient Health Questionnaire-9 items, PHQ-9;Generalized Anxiety Disorder, GAD;Insomnia Severity Index, ISI;

Secondary

MeasureTime frame
Functional magnetic resonance imaging (fMRI);Electroencephalogram (EEG);

Countries

China

Contacts

Public ContactZhang Li

Department of Psychiatry, the Second XiangYa Hospital of Central South University

505260@csu.edu.cn+86 137 8778 2104

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026