Uremic stage of chronic renal failure
Conditions
Interventions
Remimazolam tosylate group:Anesthesia with remimazolam tosilate.
Propofol group:Anesthesia with propofol.
Sponsors
The First Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-60 years; 2) Weight less than or equal to 100 kg; 3) Plan to perform kidney transplant surgery at a later date; 4) Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients who are allergic to benzodiazepines or have a history of severe allergies and family history; 2) Patients using narcotic analgesics, sedatives or non-steroidal anti-inflammatory drugs; 3) History of schizophrenia, epilepsy, Parkinson's disease or myasthenia gravis; 4) Inability to communicate due to severe dementia or speech impairment; 5) Too slow, heart rate < 50 beats/min; 6) Blood gas, electrolyte disorders; Fat metabolism disorder; 7) Did not receive hemodialysis or peritoneal dialysis within 24h before transplantation; 8) Unwilling to sign the informed consent and refuse to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative sedation and recovery.;The use of remedial sedation.;Hypotension.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events.;Renal function.; | — |
Countries
China
Contacts
Public ContactHaiying Kong
The First Affiliated Hospital, College of Medicine, Zhejiang University
Outcome results
None listed