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Effects of transcranial direct current stimulation with increased stimulation time, frequency and intensity of treatment on cognitive function in patients with schizophrenia: a randomized controlled trial

Study on the effect of transcranial direct current stimulation with increased stimulation time, frequency and intensity of treatment on cognitive function in patients with schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083439
Enrollment
Unknown
Registered
2024-04-25
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

intervention group:anodal transcranial direct current stimulation

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Participants aged 18 to 65 years old; 2. Right-handed; 3. Evaluated by at least one professional psychiatrist with associate director or above in psychiatry and diagnosed with schizophrenia (SZ) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); 4. Having a stable antipsychotic medication regimen for more than 2 weeks prior to the start of the study and throughout the entire study period; 5. Capable of understanding and completing the tests required for the study; 6. Patients and/or guardians provide informed consent.

Exclusion criteria

Exclusion criteria: 1. Presence of severe systemic diseases, including but not limited to serious liver, kidney, respiratory, cardiovascular, endocrine diseases, hematologic disorders, or neoplastic diseases; 2. Diagnosed with other primary psychiatric disorders according to DSM-V; 3. Skin lesions or dermatological conditions at the electrode site; 4. Use of metal implants or any electro-sensitive support devices; 5. Significant neurological disorders that may affect cognition or treatment response (e.g., stroke, epilepsy); 6. Pregnancy or lactation; 7. Undergoing repetitive transcranial magnetic stimulation (rTMS) or other neuromodulatory treatments; 8. Participation in another clinical trial concurrently.

Design outcomes

Primary

MeasureTime frame
Pattern Recognition Memory, PRM;Stocking of Cambridge, SOC;Spatial Working Memory, SWM;Rapid Visual Information Processing, RVP;

Secondary

MeasureTime frame
The positive and negative syndrome scale, PANSS;

Countries

China

Contacts

Public ContactLuo Qinghua

Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University

202538@cqmu.edu.cn+86 189 8361 2632

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026