Effect of esketamine combined with dexmedetomidine nasal drops on preoperative anxiety in children undergoing tonsil adenoidectomy

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400083437

Enrollment

Unknown

Registered

2024-04-25

Start date

2024-04-26

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative anxiety

Interventions

Group D:Nasal drip 2ug/kg dexmedetomidine

Group E1D:Nasal drip 1mg/kg Esketamine +1ug/kg dexmedetomidine

Group E2D:Drip 1.5mg/kg Esketamine +1ug/kg dexmedetomidine

Eligibility

Sex/Gender

All

Age

2 Years to 8 Years

Inclusion criteria

Inclusion criteria: Age 2-8 years old, ASA grade I-II, no history of anesthesia allergy or neurological diseases, BMI 18.5-28kg/m2.

Exclusion criteria

Exclusion criteria: Children with severe heart, liver, and kidney diseases; Children with neurological disorders; Children with allergies to anesthetic drugs.

Design outcomes

Primary

Measure	Time frame
The time to reach a UMSS score of two points after nasal drip;	—

Secondary

Measure	Time frame
Catheterization score;Separation score;Anesthesia induction cooperation score;	—

Countries

China

Contacts

Public ContactRenhu Li

Lu'an Hospital Affiliated to Anhui Medical University

lirenhu2008@163.com+86 139 6624 1616

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026