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Dexmedetomidine with ropivacaine in a single-injection erector spinae plane block for thoracoscopic surgery on chronic postsurgical pain

Dexmedetomidine with ropivacaine in a single-injection erector spinae plane block for thoracoscopic surgery on chronic postsurgical pain

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083431
Enrollment
Unknown
Registered
2024-04-24
Start date
2023-12-07
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic postsurgical pain

Interventions

Ropivacaine+Dexmedetomidine (experimental group):Ultrasound-guided erector spinae block at T5 segment with 0.375% ropivacaine+ dexmedetomidine (1ug/kg) injection 20ml
Ropivacaine group (control group):Ultrasound-guided erector spinae block at T5 segment with injection of 0.375% ropivacaine 20ml

Sponsors

920th Hospital of the Joint Logistics Support Force
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing thoracoscopic surgery under general anesthesia 2. ASAI-II class 3. Age = 18 years

Exclusion criteria

Exclusion criteria: 1. Patients allergic to local anesthetic drugs and dexmedetomidine 2. Severe hepatic and renal impairment or glomerular filtration rate<30mL/min or previous kidney transplantation or dialysis 3. Cardiovascular disease 4. Contraindication to regional anaesthesia 5. History of taking analgesic drugs for more than 3 months 6. Patients with a history of thoracic spine surgery and a history of thoracic surgery 7. Not cooperative, inability to understand the study or refuse to participate

Design outcomes

Primary

MeasureTime frame
The incidence of Chronic postsurgical pain;

Secondary

MeasureTime frame
NRS scores of surgical incisions at rest and during activity;Patient agitation- sedation status;Time to first additional postsurgical analgesic medication;Neuropathic pain assessment;Evaluation of the nature, severity, and effects of pain on day-to-day functioning;

Countries

China

Contacts

Public ContactLi Na

920th Hospital of the Joint Logistics Support Force

lina@kmmu.edu.cn+86 186 8700 0606

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026