postoperative mild cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age =65 years old 2. ASA grade I-III 3. Patients undergoing mechanical ventilation under general anesthesia 4. Patients undergoing hip and knee replacement at selected time
Exclusion criteria
Exclusion criteria: 1. Emergency surgery 2. The patient refused to participate in the experiment or could not sign the informed consent 3. Cognitive dysfunction was present before surgery 4. Preoperative history of restless leg syndrome, periodic limb movement disorder, and obstructive sleep apnea 5. Surgery time is later than 16:00 6. Missing watch data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative cognitive dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative extubation time;Leukocyte count;Numeric Pain Intensity Scale(Active);Numeric Pain Intensity Scale (At rest);Intraoperative mean arterial pressure fluctuation;systemic immune-inflammation index;PSQI; | — |
Countries
China
Contacts
Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing