Primary aldosteronism
Conditions
Interventions
Observation group :None
Sponsors
The First Affiliated Hospital of Chengdu Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients were =18 years old, and sex was not limited; (2) Patients who met the diagnostic and treatment guidelines for primary aldosteronism and who met the diagnostic criteria for primary aldosteronism after strict drug elution; (3) Blood pressure conditions met one of the following conditions: office blood pressure =140/90 mmHg; ambulatory blood pressure monitoring: all-day blood pressure >130/80 mmHg or daytime blood pressure >135/85 mmHg; (4) Adrenal CT showing adrenal hyperplasia, nodules, or no obvious morphological abnormalities; (5) Patients or their legal representatives signed a written informed consent form approved by the ethics committee before screening.
Exclusion criteria
Exclusion criteria: (1) Patients with primary hypertension or secondary hypertension from other causes; (2) Women who are pregnant, breastfeeding or have plans to have children in the next year; (3) Patients with serious organic diseases, especially liver and kidney dysfunction; (4) Severe allergy to contrast media; (5) Patients with other severe organic diseases with a life expectancy of <12 months; (6) The patient has been enrolled or wishes to participate in other clinical studies. During the enrollment period, the results of this study will be affected; (7) According to the judgment of the investigator, the study was considered unsuitable for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour ambulatory blood pressure;24-hour ambulatory electrocardiogram; | — |
Secondary
| Measure | Time frame |
|---|---|
| Carotid intima-media thickness;Pulse wave velocity;Ankle brachial blood pressure index;left ventricular hypertrophy;Estimated glomerular filtration rate;Microalbuminuria;Urine Albumin to Creatinine Ratio; | — |
Countries
China
Contacts
Public ContactWang Peijian
The First Affiliated Hospital of Chengdu Medical College
Outcome results
None listed