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Multiparametric MR Images-Based Prediction of Response to Neoadjuvant Immunotherapy of Rectal Cancer

Multiparametric MR Images-Based Prediction of Response to Neoadjuvant Immunotherapy of Rectal Cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083395
Enrollment
Unknown
Registered
2024-04-23
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rectal cancer

Interventions

Observation group:None

Sponsors

The Sixth Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 99 Years

Inclusion criteria

Inclusion criteria: (1) pathologically confirmed diagnosis of locally advanced rectal cancer; (2) pre-NCT and post-NCT MRI scans available within one week prior to the initiation of NCT and surgery, respectively; and (3) complete clinical and pathologic information.

Exclusion criteria

Exclusion criteria: (1) patients had previously received anticancer treatment or had other concurrent malignancies; (2) patients did not complete the entire course of NCT or did not undergo radical surgery; and (3) MRI quality was insufficient (serious motion, aliasing or rippling artefacts).

Design outcomes

Primary

MeasureTime frame
TRG;sensitivity;specificity;accurary;

Countries

China

Contacts

Public ContactYongju Yi

The Sixth Affiliated Hospital of Sun Yat-sen University

yiyj3@mail.sysu.edu.cn+86 159 1876 2358

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026