sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) 18 years old = Age = 85 years old; 2) Emergency ICU patients who meet one or more criteria for systemic inflammatory response syndrome (SIRS) [body temperature>38.3 ? or90 beats/min, respiratory rate (RR)>20 beats/min]. If it eventually develops into sepsis, it will be assigned to the sepsis group, otherwise it will be assigned to the non sepsis group.
Exclusion criteria
Exclusion criteria: 1) Age85 years old; 2) Pregnancy period; 3) Severe immune deficiency; 4) The diagnosis has been confirmed in an external hospital for more than 48 hours; 5) Patients who do not sign informed consent forms
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaminoheptanoic acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum small molecule metabolites;Clinical biochemical indicators such as liver function, renal function, procalcitonin, microcirculation indicators, blood lactate, antibiotic use, whether plasma exchange is performed, and prognostic indicators such as organ damage and 28 day mortality rate; | — |
Countries
China
Contacts
First Affiliated Hospital of Dalian Medical University