elderly patients undergoing fiberoptic bronchoscopy
Conditions
Interventions
group R:Alfentanil was first injected with a micropump for 10 µg/kg, and the first dose of remazolam was 0.2mg/kg by micropump injection after 30 seconds. The target depth of sedation was set as MOAA/
group P:Alfentanil was first injected with a micropump for 10 µg/kg, and the first dose of propofol was 1.5mg/kg by micropump injection after 30 seconds. The target depth of sedation was set as MOAA/
Sponsors
Lishui People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Aged 65-80 years, BMI 18.5-27.9kg/m2; ? ASA (American Society of anesthesiologists) grade II ~ III elderly patients undergoing fiberoptic bronchoscopy; ? The patients and their families knew the purpose of this study and voluntarily signed a written informed consent.
Exclusion criteria
Exclusion criteria: ? Patients with neurological or psychiatric diseases or communication disorders before operation; ? Preoperative diagnosis was respiratory failure (PaO2 < 60mmhg); ? New York Heart Association (NYHA) cardiac function class III or IV; ? Patients with suspected difficult airway; ? Those who have been allergic to benzodiazepines or propofol in the past, and those who have taken sedative drugs for a long time; ? Patients with severe arrhythmias, such as second or third degree atrioventricular block or significant bradycardia (HR<50 BPM).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| severe hypoxemia ;Minimum SpO2 during inspection;Maximum cough rating;Success rate of first dose sedation;Sedation success rate;Number of cases of rescue sedation;Additional sedation times; | — |
Countries
China
Contacts
Public ContactDuan Gongchen
Lishui People's Hospital
Outcome results
None listed