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Multimodal electrophysiological evaluation and rehabilitation study of neurogenic thoracic outlet syndrome

Multimodal electrophysiological evaluation and rehabilitation study of neurogenic thoracic outlet syndrome

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083349
Enrollment
Unknown
Registered
2024-04-22
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neurogenic thoracic outlet syndrome

Interventions

Conventional treatment group:? : Oral muscle relaxant (eperisone) 50mg 3 times a day
?Oral microcirculatory improving drug (dibazole), 10mg each time, 3 times a day, neurotrophic drug (mecobalamine), 500ug each time, 3 times a day
? Oral COX-2 inhibitor (celecoxib) 200mg once a day
Observation group:On the basis of conventional treatment, ultrasound guided brachial plexus nerve water separation therapy was given

Sponsors

Shenzhen Qianhai Shekou Free Trade Zone Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) The main complaint is neck, shoulder, back and upper limb pain and discomfort, the course of the disease is at least 3 months, the symptoms are repeated, completely normal when they do not occur, and the pain is unbearable when they occur. There are many inducing factors, such as cold, fatigue, prolonged time or repeated posture, sudden overexertion of the upper arm, sudden change of the head position, etc., can induce the occurrence or aggravation of symptoms; (2) It can be accompanied by some other stubborn symptoms (leading to misdiagnosis), such as stubborn singultus, pain in the chest area, repeated tinnitus, seizure dizziness, head and pillow pain, mental symptoms, indicating the middle finger end paresthesia, no serious cardiovascular, respiratory system and liver and kidney diseases; (3) Resting pain: manifested as local swelling, pain and discomfort before rest or sleep, no relief position in each part (how to put the affected limb is uncomfortable), affecting sleep, or wake up at night, neck, shoulder and limb can not fall asleep due to unspeakable discomfort; Severe patients do not dare to lie flat, or the pain is aggravated when lying flat; (4) After cervical manual massage, the pain symptoms worsened; Exclude the pain caused by other diseases (neck myofasciitis, shoulder periarthritis, nerve root type cervical spondylosis) or according to cervical spondylosis, shoulder periarthritis and other repeated treatment, the effect is not good; (5) Signs: The patient has significant tenderness at the thoracic outlet (including the supraclavicular scalene triangle and/or at the subclavian pectoral minor tendon), which may be accompanied by radiating pain in the ipilateral shoulder and upper limb; (6) Willing to cooperate with researchers, clearly understand the purpose of this clinical study, and willing to sign informed consent

Exclusion criteria

Exclusion criteria: (1) Serious consciousness, motor, cognitive, emotional disorders, affecting the implementation or evaluation of this clinical study, unable to carry out active rehabilitation treatment; (2) hepatitis, active tuberculosis, local metal foreign bodies, pregnancy, glaucoma, bone tumors, skin infections or skin lesions at closed sites; (3) Previous history of anaesthetic drug allergy, hormone drug allergy, gastrointestinal bleeding, bleeding tendency; (4) Walking instability, consider cervical spondylotic myelopathy; (5) Patients who are abnormally worried about local injection therapy and are unwilling to sign informed consent for treatment

Design outcomes

Primary

MeasureTime frame
Visual analogue pain (VAS) score;

Secondary

MeasureTime frame
Tanaka Yasuhisa Cervical spondylosis symptom scale 20 points;

Countries

China

Contacts

Public ContactWang Jun

Shenzhen Qianhai Shekou Free Trade Zone Hospital

wangjun0743@163.com+86 188 1868 1419

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026