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Magnesium Sulfate for Post-Stroke Spasticity: A Randomized Controlled Trial

Magnesium Sulfate for Post-Stroke Spasticity: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083346
Enrollment
Unknown
Registered
2024-04-22
Start date
2024-04-30
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Experimental group:Intravenous magnesium sulphate 10g

Sponsors

Jincheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Between the ages of 18 and 80; 2.Patients with clinically confirmed stroke or traumatic brain injury for more than 3 months; 3.Modified Ashworth scale score =2 for target muscles (biceps brachii, rectus femoris); 4.Baroreflex index (included values);

Exclusion criteria

Exclusion criteria: 1. high muscle tone in a single muscle group; 2. known hypersensitivity to magnesium; 3. high serum magnesium; low serum calcium 4. pregnancy and lactation; 5. serum creatinine concentration greater than 2 mg/dL; 6. urine output less than 1 mL/kg per hour; 7. electrocardiogram showing conduction block or myocardial damage; 8. systolic blood pressure less than 90 mmHg; 9. Use of drugs that are contraindicated with magnesium sulfate; 10. impaired joint mobility due to pain;

Design outcomes

Primary

MeasureTime frame
Ashworth;

Secondary

MeasureTime frame
Barthel Index;fugl-meyer assessment;Modulus of elasticity of the target muscle;

Countries

China

Contacts

Public ContactGuofa Yang

Jincheng People's Hospital

656785031@qq.com+86 186 3560 9526

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026