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Clinical randomized controlled study of probiotics in the adjuvant treatment of neonatal jaundice

Clinical randomized controlled study of probiotics in the adjuvant treatment of neonatal jaundice

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083342
Enrollment
Unknown
Registered
2024-04-22
Start date
2022-06-07
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

jaundice of the newborn

Interventions

Experimental group (Full-term):probiotics
Control group (Full-term):placebo
Experimental group (premature):probiotics
Control group (premature):placebo

Sponsors

Northwest Women and Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 30 Days

Inclusion criteria

Inclusion criteria: (1) Neonates with jaundice requiring blue light treatment (2) Gestational age 34-41 weeks (3) Birth weight is more than 2000g and less than 4000g

Exclusion criteria

Exclusion criteria: (1) Neonatal hypothyroidism (2) Trisomy syndrome (3) Maternal ABO incompatibility (4) Gastrointestinal diseases (5) Erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (6) Hemangioma (7) Cranial hematoma or hemorrhage (8) Severe asphyxia (Phase III) (9) Fetal chromosomal abnormality (10) Cyanotic congenital heart disease (11) Omphalocele (12) Premature septicemia (13) Liver failure (14) Newborn hepatitis, biliary atresia, genetic metabolic disorder and other serious primary diseases with direct increase of bilirubin

Design outcomes

Primary

MeasureTime frame
serum bilirubin;

Secondary

MeasureTime frame
Intestinal flora;

Countries

China

Contacts

Public ContactYu Xiping

Northwest Women and Children's Hospital

1807183412@qq.com+86 135 7206 1122

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026