lung injury
Conditions
Interventions
Control group (L group):Routine ECG monitoring was performed after admission, and endotracheal intubation was performed after induction of routine anesthesia. Breathing parameters: VCV: VT=7 ml/Kg* id
Experimental group (H group):Routine ECG monitoring was performed after admission, and endotracheal intubation was performed after induction of routine anesthesia. Breathing parameters: VCV: VT=7 ml/K
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-70 years; 2, ASA class I-III; 3, BMI = 30 kg/m2; 4. Patients or their legal guardians agreed to participate in this study
Exclusion criteria
Exclusion criteria: 1. Symptoms of pulmonary infection within the last 2 weeks; 2. Severe lung disease, such as chronic obstructive pulmonary disease, pleural effusion, asthma, pneumothorax, history of previous chest surgery such as lobectomy; 3. Severe cardiovascular disease and liver and kidney dysfunction; 4. Preoperative oxygen saturation = 90%; 5. Intraoperative inability to maintain oxygenation using ventilation strategies, persistent hypoxemia (SpO2 = 90% or PaO2 = 60 mmhg); 6. Unstable vital signs, including shock or severe arrhythmias; 7. Patients who are participating in other clinical trials; 8, those who are deemed unsuitable for clinical trials for other reasons by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood gas; | — |
Countries
China
Contacts
Public ContactZhou Xuelong
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed