Diabetes
Conditions
Interventions
Intervention group 1:Regular milk-Native GOS milk-Shuhua whole milk without lactose-An Tangjian milk
Intervention group 2:Native GOS milk-Shuhua whole milk without lactose-An Tangjian milk-Regular milk
Intervention group 3:Shuhua whole milk without lactose-An Tangjian milk-Regular milk-Native GOS milk
Intervention group 4:An Tangjian milk-Regular milk-Native GOS milk-Shuhua whole milk without lactose
Intervention group 5:Native GOS milk-Shuhua whole milk without lactose-Regular milk-An Tangjian milk
Intervention group 6:Shuhua whole milk without lactose-Regular milk-An Tangjian milk-Native GOS milk
Intervention group 7:An Tangjian milk-Native GOS milk-Regular milk-Shuhua whole milk without lactose
Sponsors
China Agricultural University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with pre diabetes or type 2 diabetes, aged 18 years and older (2) No clinical evidence of diabetic cardiovascular disease (diabetic cardiomyopathy), diabetic nephropathy, diabetic neuropathy, diabetic ophthalmopathy, diabetic lower-extremity arteriopathy, and diabetic foot, with background diabetic retinopathy and microalbuminuria allowed for inclusion (3) Individuals with diabetes mellitus are more stable on treatment with non-insulin hypoglycemic agents (enteric, extended- release, and generic are all available) and do not need to change medications (4) Not currently receiving insulin therapy (5) No history of food allergies or intolerances, no history of hematemesis (6) No medications affecting glucose tolerance in the last 3 months (7) Able to tolerate fasting for at least 10h (8) Contraception for women of childbearing age during the study period
Exclusion criteria
Exclusion criteria: (1) Special populations, such as pregnant women, lactating mothers, tumor patients (2) Individuals with abnormal liver and kidney function indicators during physical examination (3) Have a history of food allergies, intolerance, or dizziness, and lactose intolerance (4) Individuals with heavy physical activity and long-term sleep deprivation (5) Other diseases may impact blood glucose tolerance (6) Taking drugs other than hypoglycemic drugs that are known to affect glucose tolerance within the past 30 days (7) Medications that affect appetite and gastrointestinal function have been used in the past three months (8) Smoker (9) Unable to tolerate fasting for 10 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose;Venous blood glucose at 15, 30, 60, 90, and 120 min after meal;Venous blood insulin at 15, 30, 60, 90, and 120 min after meal; | — |
Countries
China
Contacts
Public ContactGuo Jie
China Agricultural University
Outcome results
None listed