Esophageal carcinoma
Conditions
Interventions
Experimental group:Inflatable mediastinoscope-assisted modified-Mckeown esophagectomy
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age: 18-80 years old, gender is not limited; 2) Limited resection of esophageal cancer through the right chest (1) concurrent management of left chest wall or lung disease; 2. Combined treatment of suspicious positive lymph nodes that are difficult to clean into the right chest is required; 3. Right aortic arch; 4. Right side closed chest) 3)ECOG score :0-1; 4) ASA: Level I-III 5) Major organ function is normal, that is, meet the following criteria: (1) Blood routine examination: a.HB=90g/L; b.ANC=1.5×109/L; C. PLT =80×109/L; (2) Biochemical examination: A.LB =30g/L; B.lt and AST=2.5ULN; C.bil =1.5ULN; d. Plasma Cr=1.5ULN or creatinine clearance (CCr)=60ml/min; 6) Doppler ultrasound evaluation: left ventricular ejection fraction (LVEF) = the lower limit of normal value (50%); 7) Women of reproductive age should agree to use contraceptives (such as Iuds, contraceptives or condoms) during the study period and for 6 months after the study ends; Have a negative serum or urine pregnancy test within 7 days prior to study enrollment and must be a non-lactating patient; Men should consent to patients who must use contraception during the study period and for 6 months after the end of the study period; 8) The subjects voluntarily joined the study, signed the informed consent, had good compliance, and cooperated with the follow-up.
Exclusion criteria
Exclusion criteria: 1) Pregnant or lactating women; 2) Patients who have had other malignancies within 5 years (except basal cell carcinoma of the skin and carcinoma in situ of the cervix that has been cured); 3) Patients who have a history of psychotropic drug abuse and cannot quit or have mental disorders; 4) Patients who have participated in clinical trials of other drugs within four weeks; 5) Severe spinal deformity; 6) Patients with concomitant diseases (such as acute myocardial infarction, cerebral infarction, pulmonary embolism, etc.) that, according to the judgment of the investigator, seriously endanger the safety of the patient or affect the completion of the study; 7) Those deemed unsuitable for inclusion by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| anastomotic leakage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Conversion thoracotomy/laparotomy;operation duration;intraoperatve blood soss;Other perioperative complications; | — |
Countries
China
Contacts
Public ContactLi Xiangnan
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed