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Study of the correlation between succinate and the degree of lung injury and prognosis in patients with acute lung injury

The value of succinate determination in predicting the degree of lung injury and prognosis in patients with acute lung injury

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083317
Enrollment
Unknown
Registered
2024-04-22
Start date
2024-04-22
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lung injury

Interventions

Sponsors

The First Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for patients with acute lung injury in the Intensive Care Unit: (i) Age ?18 years old; (ii) BMI 18.5-30 kg/m2; (iii) Patients with acute lung injury with diagnosed intrapulmonary factors who received endotracheal intubation therapy; (iv) Oxygenation index (PaO2/Fi02) <300 mmHg; and (v) Signed informed consent. Inclusion criteria for elective surgery patients with good pulmonary function in the Anesthesia department: ? Age ?18 years old; ? BMI 18.5-30 kg/m2; ? Good lung function and intended to receive general anesthesia by tracheal intubation; ? Signed informed consent.

Exclusion criteria

Exclusion criteria: ? Patients, family members, or legal guardians refused the test; ? Suffering from serious heart, lung, liver, kidney, and other chronic diseases, combined with acute and chronic cardiac insufficiency, and coagulation abnormalities; ? Did not complete the specimen collection.

Design outcomes

Primary

MeasureTime frame
Succinic acid;Lung injury score;

Secondary

MeasureTime frame
Lung microbiome;

Countries

China

Contacts

Public ContactZeng Kai

The First Affiliated Hospital of Fujian Medical University

fymzk6822@163.com+86 130 5529 1712

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026