bladder pain syndrome/interstitial cystitis
Conditions
Interventions
Control group:Essential Medicines
treatment group:Essential Medicines + Ozone Water Therapy
Sponsors
Second Hospital of Tianjin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: ?Refer to the IC diagnostic criteria developed by the Guidelines for the Diagnosis and Treatment of Andrology Diseases in Urology in China;? Age 18~85 years old (inclusive), male or female;? In the awake state, the bladder capacity is > 150 mL (there is no urgency to urinate when the bladder is filled with 150ml of liquid);? The previous drug treatment or physical therapy effect was not good, and the drug has been stopped for 2 weeks;? The 24-hour average pain score was greater than 4 points and less than 8 points.? Able to comply with study and follow-up procedures;? Voluntarily participate in this clinical trial and sign the informed consent form of the subject;
Exclusion criteria
Exclusion criteria: ? Other patients with chemical cystitis or tuberculous cystitis; ? People with urinary tract infection; ? Bladder tumors; ? In the awake state, the bladder capacity < 150 mL;? Pregnant women;? Allergic constitution,G6PD deficiency(favism)and hyperthyroidism are contraindications to ozone therapy; ? Patients treated with intravenous copper or iron are contraindicated to ozone therapy; ? Those with major diseases of the heart, liver and other systems are excluded;? Exclusion of those with poor compliance;? Those who have participated in other clinical trials within 1 month before the start of this trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale(VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Interstitial Cystitis Symptom Index Score (ICSI);Interstitial Cystitis Problem Index Score (ICPI);Quality of Life ( QOL);physically unclonable function (PUF);voiding diary(VD); | — |
Countries
China
Contacts
Public ContactHuixing Wang , Yang Tang
Second Hospital of Tianjin Medical University
Outcome results
None listed