Effect of chondroitin sulfate combined with glucosamine on rehabilitation of patients after total knee replacement

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400083292

Enrollment

Unknown

Registered

2024-04-19

Start date

2024-04-20

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee arthroplasty

Interventions

Experimental group:Combined use of 1000mg glucosamine and 1000mg chondroitin sulfate+routine rehabilitation

Control group:Placebo+routine rehabilitation

Eligibility

Sex/Gender

All

Age

55 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The age is 55~75 years old. 2. No serious heart and lung disease can tolerate surgery. 3. Conscious and stable. 4. All of them fill in the informed consent form and are willing to complete the whole experiment.

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to any component in the study nutritional supplement. 2. Cancer patients. 3. BMI=40kg/m2. 4. Sensory disorder or abnormality of lower limbs. 5. Malignant tumor of bone or soft tissue or peripheral neuropathy involving lower limbs.

Design outcomes

Primary

Measure	Time frame
Isokinetic muscle strength test;	—

Secondary

Measure	Time frame
Pain visual analogue scale;Range of motion;IL-1ß;IL-6;	—

Countries

China

Contacts

Public ContactSong Yufeng

The Second Hospital of Shanxi Medical University

songyufeng@sxmu.edu.cn+86 136 3347 5405

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026