AIDS
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age =18 years old; (2) WB confirmation test is positive: at least two env bands (gp41 and gp160/gp120) appear, or at least one env band and p24 band appear simultaneously; (3) The duration of ART treatment exceeds 5 years; (4) Patients diagnosed with three common cardiovascular diseases (hypertension, moderate and severe hyperlipidemia, coronary heart disease) were selected as the experimental group, and patients excluded from cardiovascular disease were selected as the control group. Baseline characteristics such as age, gender, and HIV diagnosis time of the control group were matched with those of the experimental group; (5) Voluntarily sign informed consent and ensure follow-up; (6) unplanned relocation from Beijing during the course of the test.
Exclusion criteria
Exclusion criteria: (1) Patients who are allergic to or intolerant to therapeutic drugs; (2) Active opportunistic infection (stipulated in the National AIDS Treatment Guidelines) or AIDS-related malignant tumor at the time of enrollment; Or had an opportunistic infection within 3 months before inclusion, and the condition was still unstable within 2 weeks before inclusion; (3) Patients with serious mental and neurological diseases; (4) pregnant and lactating women; (5) Failure to comply with the experimental agreement and withdrawal of the informed consent; (6) Those found in the course of research to have lied to the data or concealed their true personal situation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-6; | — |
Secondary
| Measure | Time frame |
|---|---|
| antiretroviral therapy;CD4+T cell count;Viral load;demographic baseline characteristics; | — |
Countries
China
Contacts
Beijing Youan Hospital, Capital Medical University