postoperative nausea and vomiting
Conditions
Interventions
experimental group :The sevoflurane drug dose was adjusted to maintain bispectral index range of 40-45
Control group:The sevoflurane drug dose was adjusted to maintain bispectral index range of 55-60
Sponsors
Qilu Hospital, Shandong University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Female patients diagnosed with thyroid cancer; (2) Age: 18-65 years old; (3) BMI:18-30kg/m2; (4) American Association of Anesthesiologists (American Society of Anesthesiologists, ASA) grade I-II; (5) Patients who plan to have unilateral radical resection of thyroid cancer surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: (1) Patients with preoperative history of motion sickness or PONV; (2) Patients with gastrointestinal diseases, craniocerebral diseases, oogenic diseases that can cause nausea and vomiting or have received chemotherapy in the past few weeks; (3) Taking antiemetic drugs in the ward within 24 hours before surgery; (4) Patients with serious neurological and mental diseases; (5) Severe heart, lung, cerebrovascular, or liver and kidney function damage; (6) Do not agree to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of PONV at 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of PONV at other postoperative time points;The use of remedial antiemetic medication at various time points;visual analogue scale, VAS;Use of intraoperative cardiovascular active drugs;Time of awakening;Time of extubation;The occurrence of respiratory depression, hypotension, bradycardia and chills; | — |
Countries
China
Contacts
Public ContactFeng Qi
Qilu Hospital, Shandong University
Outcome results
None listed