anal disease
Conditions
Interventions
Control group :Sufentanil (2ug/kg) was added to patient-controlled intravenous analgesia pump
intervention group:Sufentanil (2ug/kg) and esketamine (50mg) were added to patient-controlled intravenous analgesia pump
Sponsors
People's Hospital of Ningxia Hui Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Patients =18 years of age who are undergoing anal surgery 2) American Society of Anesthesiologists Physical Status ?-?. 3) BMI 18-30 kg/m2. 4) Patients use patient-controlled intravenous analgesia (PCIA) after surgery.
Exclusion criteria
Exclusion criteria: 1) Patients with contraindications associated with esketamine. 2) Patients with pre-existing schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis. 3) Patients with severe dementia, speech impairment, coma, etc., who are unable to complete the preoperative assessment. 4) Patients with preoperative sleep disturbance (Pittsburg Sleep quality score =7). 5) Patients currently using sleeping pills or antidepressants. 6) Body mass index (BMI) = 30 kg/m 2. 7) Patient refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| AIS;HADS;The dosage and frequency of postoperative remedial analgesia;Postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactYe Zhenhai
People's Hospital of Ningxia Hui Autonomous Region
Outcome results
None listed