mild to moderate common mental disorders, including depression, anxiety, and insomnia
Conditions
Interventions
individualized music therapy group (n=30 for S3 & n=45 for S4):(the frequency of treatment may be adjusted according to the finalized individualized music treatment plan) individualized music therapy
music therapy as usual group (n=40 for S2 & n=30 for S3):(the frequency of treatment may be adjusted according to the finalized individualized music treatment plan) traditional music therapy, widely u
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Health Control Group: ?Matched with the patient group in terms of age, gender, ethnicity, and handedness; ?Currently do not meet the DSM-5 diagnostic criteria for any mental disorders, such as Major Depressive Disorder, Bipolar Disorder, Schizophrenia, etc; ?No history of mental disorders within three generations of the family; ?Capable of understanding and cooperating with the study procedures; ?Informed and voluntarily participating in this study, with informed consent signed by the participant themselves. Depression Group: ?Aged 18-60 years; ?Meet DSM-5 criteria for mild to moderate major depressive episodes; ?Hamilton Depression Rating Scale (HAMD-17) score between 7 and 23; ?Capable of understanding and cooperating with the study procedures; ?Informed and voluntarily participating in this study, with informed consent signed by the participant themselves. Anxiety Group: ?Aged 18-60 years; ?Meet DSM-5 criteria for generalized anxiety disorder; ?Hamilton Anxiety Rating Scale (HAMA) score between 7 and 21; ?Capable of understanding and cooperating with the study procedures; ?Informed and voluntarily participating in this study, with informed consent signed by the participant themselves. Insomnia Group: ?Aged 18-60 years; ?Meet DSM-5 criteria for sleep disorders; ?With difficulty in initiating sleep as the primary symptom; ?Exhibits persistent insomnia (duration = 3 months); ?Capable of understanding and cooperating with the study procedures; ?Informed and voluntarily participating in this study, with informed consent signed by the participant themselves.
Exclusion criteria
Exclusion criteria: Health Control Group: ?Current somatic diseases affecting the structure and function of the central nervous system or other vital organ systems; ?Women who are pregnant or breastfeeding; ?Individuals with hearing impairments that, as assessed by researchers, impede their ability to participate in the study procedures; ?Other conditions deemed by researchers as inappropriate for participation in this study. Depression Group: ?Co-morbid psychiatric disorders such as schizophrenia, bipolar disorder, anxiety disorders, obsessive-compulsive disorder, eating disorders, somatic symptom disorders, and substance use and behavioral addictions; ?Co-morbid somatic diseases affecting the structure and function of the central nervous system or other vital organ systems; ?Women who are pregnant or breastfeeding; ?Individuals with hearing impairments that, as assessed by researchers, impede their ability to participate in the study procedures. Anxiety Group: ?Co-morbid psychiatric disorders such as schizophrenia, depression, bipolar disorder, obsessive-compulsive disorder, eating disorders, somatic symptom disorders, and substance use and behavioral addictions; ?Co-morbid somatic diseases affecting the structure and function of the central nervous system or other vital organ systems; ?Women who are pregnant or breastfeeding; ?Individuals with hearing impairments that, as assessed by researchers, impede their ability to participate in the study procedures. Insomnia Group: ?Co-morbid psychiatric disorders such as schizophrenia, bipolar disorder, depression, anxiety disorders, obsessive-compulsive disorder, eating disorders, somatic symptom disorders, and substance use and behavioral addictions; ?Other clear physical symptoms affecting sleep quality, such as pain; ?Co-morbid somatic diseases affecting the structure and function of the central nervous system or other vital organ systems; ?Women who are pregnant or breastfeeding; ?Individuals with hearing impairments that, as assessed by researchers, impede their ability to participate in the study procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Montgomery-Asberg Depression Rating Scale (MADRS) score;Change in Hamilton Anxiety Scale (HAMA) score;Change in Pittsburgh Sleep Quality Index (PSQI) score;Change in Clinical Global Impression-Severity (CGI-S) score;Changes in electroencephalographic (EEG) characteristics; | — |
Countries
China
Contacts
Public ContactWei Jing
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed