Renal anemia
Conditions
Interventions
High-Ferritin :Reactive iron supplementation, maintaining ferritin 400ng/ml
Low-Ferritin :Reactive iron supplementation, maintaining ferritin 100ng/ml
Mid-Ferritin :Reactive iron supplementation, maintaining ferritin 200ng/ml
Sponsors
Department of Nephrology, Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1: Receive regular hemodialysis for more than 6 months 2: Adequate dialysis (=3 times per week and =10 hours/week) 3: Use ESA to treat anemia 4: Ferritin 200~500ng/mL 5: Hb 100~120g/L
Exclusion criteria
Exclusion criteria: 1: Iron allergy or previous inability to receive intravenous iron therapy for any reason 2: rHuEPO dosage >300U/Kg/W or Daepotin a>1.5ug/Kg/W 3: There were significant drug-related adverse reactions during enaldostat induction 4: abnormal liver function 5: Previous diagnosis of any type of myeloproliferative disease 6: History of malignant tumor 7: Untreated proliferative retinopathy with fundus hemorrhage 8: Within 3 months of gastrointestinal bleeding 9: Diagnosis of thrombotic, embolic disease within 3 months 10: Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hb/AAD ; | — |
Secondary
| Measure | Time frame |
|---|---|
| control rates of Hb ;Adverse reactions to intravenous iron ; | — |
Countries
China
Contacts
Public ContactNan Hu
Peking University First Hospital
Outcome results
None listed