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Effect of B vitamin therapy on gut microbiota and delirium severity in elderly patients with delirium

Effect of B vitamins therapy on gut microbiota and delirium severity in elderly patients with delirium

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400083213
Enrollment
Unknown
Registered
2024-04-18
Start date
2024-04-25
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium

Interventions

B vitamins intervention group:Vitamin B1 tablets (2 tablets/dose, 3 times a day) + Vitamin B complex tablets (3 tablets/dose, 3 times a day) Treatment: 1 months of continuous use.
Blank control group:None

Sponsors

The First Affiliated Hospital of Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: ? Age = 65 years old, no gender limitation; ? Delirium assessed by the Chinese version of the 3min Delirium Diagnostic Scale (3D-CAM); ? No surgical treatment in the last six months; ? Agreed to participate in the program and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: ? recent (<1 month) history of antibiotic, probiotic or prebiotic administration; ? gastroenteroscopy or enema within one month; ? previous or ongoing fecal colony transplantation treatment; ? illnesses affecting cognitive assessment or inability to cooperate; ? co-morbidities with malignant tumors; ? lack of consent to participate in the project; and ? other conditions deemed inappropriate for enrollment by the researcher.

Design outcomes

Primary

MeasureTime frame
Delirium;Severity of delirium;Gut microbiota;

Secondary

MeasureTime frame
Number of delirium attacks within 1 month;Duration of each delirium;Adverse drug reactions;Serum B vitamins;Delirium subtype;

Countries

China

Contacts

Public ContactXiaoxuan Ning

The First Affiliated Hospital of Air Force Medical University

ningxx01@fmmu.edu.cn+86 136 7922 0705

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026