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The association of serum Isthmin-1 and blood pressure in hypertension: a cross-sectional study

The regulatory role of Isthmin-1 in hypertension

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083204
Enrollment
Unknown
Registered
2024-04-18
Start date
2023-08-01
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Healthy control group:None

Sponsors

The Third Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years; 2. Newly diagnosed patients with hypertension are defined as having systolic blood pressure (SBP) = 140 mmHg and/or diastolic blood pressure (DBP) = 90 mmHg (blood pressure measured three times in different settings).

Exclusion criteria

Exclusion criteria: 1. Suffering from diabetes and secondary hypertension; 2. Patients with severe acute and chronic diseases such as cardiovascular system, respiratory system, urinary system, nervous system, bone and motor system, blood and immune system, endocrine system, eyes, ears, nose and throat; 3. Patients with infectious diseases and infectious diseases who are not suitable for enrollment; 4. Pregnant or expectant women, etc.

Design outcomes

Primary

MeasureTime frame
Isthmin-1;Blood pressure;

Secondary

MeasureTime frame
Urine Na+ concentration, urine volume;Height, weight;FBG (fasting blood-glucose);Blood lipid, liver function, kidney function, blood routine examination;HOMA-IR;

Countries

China

Contacts

Public ContactYang Jian; Deng Chunyan

The Third Affiliated Hospital of Chongqing Medical University

yangjianac@163.com+86 137 0838 3337

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026